An epidemic of highly pathogenic avian influenza virus of subtype H5N1 Asia (HPAIV H5N1) broke out again in mid February 2013 in a farm of Bandenburg, Germany. On 16.Febr. 2013 14.500 ducks had to be culled. Germany had been free of avian influenza virus for three years. Veterinarians say that there is no danger for humans, however the H5N1 virus threatened poultry holdings worldwide since 1997.