Dunn et al. 2012 describe a multi-species microarray platform and the array-Comparative Genomic Hybridization (aCGH) of the genomes of several Saccharomyces cerevisiae and S. paradoxus, S. mikatae, S. kudriavzevii, S. uvarum, S. kluyveri and S. castellii. [1]
The technique is able to identify variations in copy number among different yeasts and determines the evolutionary relationships without sequencing the whole genome.