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28.06.2008 Anti-obesity drug Acomplia
German health insurance do not pay for acomplia and scientist issues warn for late-effects [1]
The
Lower House of the German Parliament (Bundestag) decided that German
health insurance will not pay for Acomplia classifying the drug as
lifestyler. Rimonabant is the active ingredient of Acomplia. The drug
was banned in USA because of depression and suicide side effects, but
is approved in France, Germany and UK. [2]
Acomplia acts on the central nerve system, blocking certain receptors.
This is of concern for the neurobiologist Andreas Zimmer from the
University Bonn, Germany. He found that a special type of mice which
received Acomplia had a reduced lifespan, presented epilepsy and a loss
of nerve cells in the brain was found.
The producer of the
drug, Sanofi-Aventis, argues that effects in animals cannot be
translated to human physiology. Zimmer says that the 2 an 3 years
studies presented by Sanofi-Aventis were to short to show late-effects.
The company expects a revenue from Acomplia of up to 5 billion
Dollar/year.
[1] ARD. Tagescschau.de: Entscheidung über Schlankmacherpille. Kassen müssen nicht für "Acomplia" zahlen. 28.06.2008
http://www.tagesschau.de/wirtschaft/meldung93178.html
[2]
BBC: Weight loss pill warning issued. A weight-loss drug used by
thousands is unsafe for those also taking antidepressants, health
watchdogs warn. 19.07.2007
http://news.bbc.co.uk/2/hi/health/6907160.stm
28.06.2008: Vitamin D deficiency
Low vitamin D status increase risk of a series of causes of mortality [1]
Harald
Dobnig and colleagues 2008 in a study in Graz, Austria suggest 20 - 30
ng/mL as the minimum desirable serum level of 25-hydroxyvitamin D. It
is estimated that up to 60% of the populations in North America and
other parts of the world are vitamin D deficient.
The study
found vitamin D levels varying from 12 ng/mL to 22.7 ng/mL. The low
25-hydroxyvitamin D levels increased risk of all cause mortality and
inflammation (C-reactive protein and interleukin-6 levels), oxidative
burden (serum phospholipid and glutathione levels) and cell adhesion
(vascular cell adhesion molecule 1 and intercellular adhesion molecule
1 levels).
The authors write that low 25-hydroxyvitamin D and
1,25-dihydroxyvitamin D levels increase the risk of all-cause and
cardiovascular mortality. They call for intervention trials using
vitamin D as final confirmation of the risk relationship with vitamin D
deficiency.
Low levels of 25(OH)D with higher risk of myocardial infarction [2]
Edward
Giovannucci and colleagues in a study in 2008 found an association of
low levels of 25(OH)D with higher risk of myocardial infarction.
[1]
Harald Dobnig; Stefan Pilz; Hubert Scharnagl; Wilfried Renner; Ursula
Seelhorst; Britta Wellnitz; Jürgen Kinkeldei; Bernhard O. Boehm; Gisela
Weihrauch; Winfried Maerz: Independent Association of Low Serum
25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D Levels With All-Cause
and Cardiovascular Mortality. Arch Intern Med. 2008;168(12):1340-1349.
http://archinte.ama-assn.org/cgi/content/abstract/168/12/1340
[2]
Giovannucci, Edward; Liu, Yan; Hollis, Bruce W.; Rimm, Eric B.:
25-Hydroxyvitamin D and Risk of Myocardial Infarction in Men. A
Prospective Study. Arch Intern Med. 2008;168(11):1174-1180.
http://archinte.ama-assn.org/cgi/content/abstract/168/11/1174?
28.06.2008: New phthalate testing
method revealed toxic migration from recycled cartons to hot foods
[1]
Recycled paper and cardboard may contain toxic inks, adhesives and other dyes which may migrate to foods like pizzas, curry sausages which heat up the cardboard. For this reason recycled materials are not permitted in pizza boxes in Italy. Phthalates such as diisobutyl phthalate were found in pizza boxes in 2008 by Monica Bononi using a new developed testing method for phthalate migration in paper and cardboards.
The new method is a useful tool for the packaging industry to measure the amount of DIBP emanating from recycled cardboard, paper and seals for caps for glass jars.
German manufacturers and processors of paper and cardboard recently decided to stop using products containing DIBP due to safety concerns.
The Australian consumer group CHOICE found in June 2008 that more than half of baby foods in jars were contaminated by phthalate used as plasticizer in the seal of the cap. The group says that there is no immediate health danger to individuals, however, it is the long-term health implications of plasticisers migrating into foods which is of concern.
CHOICE calls for the food industry to find safe alternatives to epoxidised soybean oil(ESBO) and phthalates, and regulators should sets limits for plasticisers in food. [2]
[1] Bononi, Monica; Tateo, Fernando: Identification of diisobutyl phthalate (DIBP) suspected as possible contaminant in recycled cellulose for take-away pizza boxes. Packaging Technology and Science. Doi:10.1002/pts.805
http://www3.interscience.wiley.com/journal/116844643/abstract?CRETRY=1&SRETRY=0
[2] CHOICE:
Plasticisers, CHOICE tested foods in glass jars and found
contaminants from the plastic used to seal the lids. Online 06/08.
http://www.choice.com.au/viewArticle.aspx?id=106380&catId=100228&tid=100008&p=1&title=Plasticisers
27.06.2008: EU panel says synthetic zeaxanthin as an ingredient in food supplements is not safe [1]
The EU Panel on Dietetic Products, Nutrition and Allergies found that the safety could not be established for synthetic Zeaxanthin as an ingredient in food supplements for a level of up to 20 mg/person/day.
According to the Panel, in European countries, the average intake level of zeaxanthin via food was estimated to be between 0.2 and 0.9 mg/day and for people with a high intake of zeaxanthin-rich vegetables and fruits this could result in a level of 1.8 mg/day (95th percentile). The proposed use levels of up to 20 mg/person/day of synthetic zeaxanthin as an ingredient in food supplements would lead to intake levels up to 100 times higher than the average intake from natural sources.
These intake levels are within the range of the group ADI 0-2 mg/kg body weight for lutein and synthetic zeaxanthin as established by JECFA. However, in the opinion of the Panel, the toxicological data on synthetic zeaxanthin are not sufficient to derive an acceptable daily intake.
Zeaxanthin and eye diseases [2]
Zeaxanthin is one of the two carotenoids contained within the retina of the eye.
Within the central macula, zeaxanthin is the dominant component, whereas in the peripheral retina, lutein predominates.
As a food additive, zeaxanthin is a food colour wtith E number E161h.
Zeaxanthin is one of the most common carotenoid alcohols found in nature. It is the pigment that gives corn, saffron, and many other plants their characteristic colour. Zeaxanthin breaks down to form picrocrocin and safranal, which are responsible for the taste and aroma of saffron. Sources of zeaxanthin and lutein are eggs, spinach and other green vegetables.
Low plasma concentrations of lutein and zeaxanthin may increase the risk of developing age-related macula degeneration (AMD). Some studies say that supplemental lutein and/or zeaxanthin could reduce the risk of AMD [3] and cataract.
The Blue Mountains Eye Study [4]
In an Australian cohort study, Jennifer Tann and colleagues 2008 found that higher dietary lutein and zeaxanthin intake reduced the risk of Age-Related Eye Disease AMD, confirming finding of protective influences from zinc against AMD. Higher beta-carotene intake were found by the authors to increase the risk of AMD.
[1] Scientific Opinion of the Panel on Dietetic Products Nutrition and Allergies on a request from the European Commission on the safety of synthetic Zeaxanthin as an ingredient in food supplements. The EFSA Journal (2008) 728, 1-28.
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1178717463740.htm
[2] Wikipedia: Zeaxanthin
http://en.wikipedia.org/wiki/Zeaxanthin
[3] Age-Related Eye Disease Study Research Group, SanGiovanni. John Paul; Chew, Emily Y. , et al.: The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. 22. (2007) Arch Ophthalmol 125 (9) 1225-1232.
http://archopht.ama-assn.org/cgi/content/abstract/125/9/1225
[4] Tan, Jennifer S.L.; Wang, Jie Jin; Flood, Victoria; Rochtchina, Elena; Smith, Wayne; Mitchell, Paul: Dietary antioxidants and the long-term incidence of age-related macular degeneration: the Blue Mountains Eye Study. Ophthalmology 2008 Feb;115(2):334-41. Epub 2007 Jul 30.
http://www.ncbi.nlm.nih.gov/pubmed/17664009?ordinalpos=1&itool=EntrezSystem2.PEntrez.
Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_
RA&linkpos=1&log$=relatedarticles&logdbfrom=pubmed
No support for prevention of AMD by omega-3 fratty acids [1]
Chong and colleagues 2008 in a systematic review and meta-analysis the evidence on dietary omega-3 fatty acid and fish intake in the primary prevention of age-related macular degeneration (AMD found that findings of this meta-analysis suggests that consumption of fish and foods rich in omega-3 fatty acids may be associated with a lower risk of AMD, however, there is insufficient evidence from the current literature to support their routine consumption for AMD prevention.
No relation between alcohol consumption and AMD [2]
Boekhoorn and colleagues in the Rotterdam study 2008 found no relationship between overall or specific alcohol consumption and risk of aging macula disorder (AMD), a synonym for age-related macular degeneration. The authors concluded that alcohol consumption is not a risk factor for AMD.
[1] Chong, Elaine W-T.; Kreis, Andreas J.; Wong, Tien Y.; Simpson, Julie A.; Guymer, Robyn H.: Dietary omega-3 Fatty Acid and Fish Intake in the Primary Prevention of Age-Related Macular Degeneration. A Systematic Review and Meta-analysis. Arch Ophthalmol. 2008;126(6):826-833.
http://archopht.ama-assn.org/cgi/content/short/126/6/826
[2] Boekhoorn, Sharmila S. ; Vingerling, Johannes R.; Hofman, Albert; de JonSg, Paulus T. V. M.: Alcohol Consumption and Risk of Aging Macula Disorder in a General Population
The Rotterdam Study. Arch Ophthalmol. 2008;126(6):834-839.
http://archopht.ama-assn.org/cgi/content/abstract/126/6/834
26.06.2008: Coffee and tea may reduce risk of a certain type of stroke [1]
Larsson and colleagues 2008 in a large, prospective, observational study using data from the Finnish Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study showed that smokers who consumed 8 or more cups of coffee per day, and those who drank 2 or more cups of black tea daily had reduced cerebral infarction risk.
The authors concluded that high consumption of coffee and tea may reduce the risk of cerebral infarction among men but not to other types of stroke, such as intracerebral hemorrhages, subarachnoid hemorrhages, and unspecified strokes.
[1] Larsson, Susanna C.; Männistö, Satu; Virtanen, Mikko J.; Kontto, Jukka; Albanes, Demetrius; Virtamo, Jarmo: Coffee and Tea Consumption and Risk of Stroke Subtypes in Male Smokers. Stroke. 2008;39:1681-1687; published online before print March 27 2008, doi:10.1161/STROKEAHA.107.504183
http://stroke.ahajournals.org/cgi/content/abstract/39/6/1681
25.06.2008: The Radioactive waste leakage at the final disposal site Asse 2 near Wolfsburg, Germany. [1]
Leaking barrels with high radioactive waste in a salt cavern in Germany in 700 meters caused a spill which may affect drinking water of the region. The site had to be closed because of the high radioactivity of the site endangering engineers. Cesium-127 is heavily contaminating water which circulates through the walls of the cavern.
Experts say that contamination of drinking reservoir of the nearby region Harz for the coming generation is very likely to occur.
Electricity from nuclear power plants is therefore a deadly choice for humanity.
The German government tries to play down the dangers for the region to avoid panic of the population. However, experts says that there is no solution how the contamination of the whole region can be avoided.
[1] Spiegel Online: ATOMMÜLLENDLAGER ASSE Expertengruppe soll über "Schweizer Käse" beraten
http://www.spiegel.de/wissenschaft/mensch/0,1518,561832,00.html
25.06.2008: Fish oil prices are kept high embedded in a climate of overall increasing prices [1]
Soy beans, fish meal and oil are basics of animal feed. Their price influences global food trade prices.
According to a market report of FAO Globefish The cost of many vegetable oils has doubled in the past year as a result of a confluence of factors, including use of crops for biofuels and insufficient harvests.
Fish oil is actually a by-product of the fish meal industry, with the protein part used largely for animal feed. The price of fish oil is closely related to the fluctuation of the price of vegetable oil.
Up to 80% of fish oil is used in aquaculture as feed for farmed fish. As vegetable oils gets expensive, fish farmers have opted for the comparatively cheaper fish oil instead, increasing the demand for fish oil.
Fish oil: The price of fish oil rose from US$800 per metric tonne in February 2007 to $2200 per metric tonne in February 2008.
Fish meal: Fish meal prices of US$ 1 210/tonne is about US$ 100/tonne 6% below the price level one year ago due to little buying interest in China. Prices for fish meal and fish oil will remain high in a climate of overall increasing vegetable meal prices, creating an environment of higher prices.
The present price level of soy meal is US$ 500/tonne is almost double the price level of one year ago.
New Code of Responsible Practice (CORP) [1] [2]
This code is being developed by the International Fish meal and Fish Oil Organisation (IFFO), which represents the fish meal and fish oil industry worldwide, is developing a new Code of Responsible Practice (CORP). Fish meal and fish oil producers will be able to prove that their products are traceable, high quality marine products which are manufactured safely using fish from responsibly managed fisheries. Producers should be able to enter the audit process early in 2009.
The EU and Japan monitor fish meal to ensure it is free of land animal material.
HACCP shemes: HACCP schemes are usually in place to control safety and quality of the production. This involves outside inspectors who ensure critical control points are correctly identified and controls carefully monitored and recorded e.g. product temperature, moisture, microbial count etc.
IFSA quality assurance scheme: Exporters to the European Union should adopt the IFSA.International Feed Standard Alliance (IFSA) quality assurance scheme. This covers quality assurance from raw material through the factory, storage and transport to the end user. It includes the Dutch GMP+ and UK Femas schemes and is expected to become the main quality assurance scheme for raw materials across Europe. [3]
Production and quality : The production and quality controls of fish meal and oil are described by FAO . [4] [5]
[1] FAO Globefish: Fishmeal Market Report - June 2008. Fishmeal prices up, but might decline soon.
http://www.globefish.org/index.php?id=4535
[2] International Fishmeal and Fish Oil Organisation (IFFO): Production
http://www.iffo.net/default.asp?fname=1&sWebIdiomas=1&url=174
[3] International Feed Safety Alliance (IFSA) IFIS IFSA Feed Ingredients Standard
April 2007
http://www.ifsa-info.net/lmbinaries/ifis.pdf
[4] FAO: The production of fish meal and oil.
http://www.fao.org/docrep/003/x6899e/X6899E00.HTM
[5] FAO: Fish oil quality
http://www.fao.org/docrep/003/x6899e/X6899E11.htm#10.2.6%20Fish%20oil%20quality
24.06.2008: Infant formula and follow-up formula may contain harmful 3-MCPD fatty acid esters [1]
The substance 3-monochloropropane-1,2-diol (3-MCPD) may be formed when fat-containing foods that also contain salt are exposed to high temperatures during production. It has been detected in numerous heated foods, for instance in dark brown toast. During the production of fats and oils, 3-MCPD fatty acid esters may be formed from 3-monochloropropane-1,2-diol when the fats and oils are heated to high temperatures.
Significant amounts of 3-MCPD fatty acid esters have now been detected by food control authorities in numerous edible fats and fat-containing foods, for instance in infant formula and follow-up formula. The Federal Institute for Risk Assessment (BfR) has assessed the detected levels from the health angle and recommended that concerted action be taken to lower the levels of 3-MCPD esters in infant formula and follow-up formula. The Institute recommends that mothers who are unable to breastfeed their infants and give them infant formula should continue to do so.
The latest studies by the official food control authorities identified high levels of 3-MCPD fatty acid esters for the first time in refined edible fats like margarine and oil and in fat-containing foods including infant formula and follow-up formula.
The BfR says that the TDI value of 2 μg/kg body weight for 3-MCPD is exceeded in adults with a high consumption of refined vegetable fats. This applies in particular to infants who ingest formula and follow-up formula (to the extent that the TDI concept is also applied to infants for whom it normally does not apply in the first months of life).
BfR believes there is a need for action to reduce the levels of 3-MCPD esters in edible fats and fat-containing foods as there is no alternative to infant formula and follow-up formula for babies who are not breastfed, aside from breast milk from other mothers. BfR advises mothers who are unable to breastfeed their babies to continue feeding their infants the commercially available products. Cow milk or the milk of other domestic animals is not a viable alter-native as it does not contain some essential nutrients which infants need for their development.
The BfR believes there is a need for action to reduce the levels but does not see any acute health risk.
[1] Federal Institute for Risk Assessment (BfR) Infant formula and follow-up formula may contain harmful 3-MCPD fatty acid esters. BfR Opinion No. 047/2007, 11 December 2007
http://www.bfr.bund.de/cm/245/infant_formula_and_follow_up_formula_may_contain_harmful_
3_mcpd_fatty_acid_esters.pdf
24.06.2008: Competitiveness of the European Food Industry. [1]
The first meeting of the High Level Group (HLG) on the Competitiveness of the Agro-Food Industry today will help pave the way to boosting the performance of this important sector in Europe. Their task is to identify and address issues that determine the competitiveness of the Agro-Food industry and to formulate a set of recommendations to achieve predictable and stable framework conditions for years to come.
The competitiveness of Europe's food industry is weak compared to the US and Canada, and at a similar level to Australia's and Brazil's, according to the Commission's report, Competitiveness of the European Food Industry: An economic and legal assessment. [2]
Priority topics for the HLG are, amongst others: competitiveness issues, needs for innovation and research & development, sustained support for small and medium sized enterprises (SMEs), simplifying food legislation while ensuring a high level of food safety, new means of sustainable production, multilateral and bilateral trade agreements and ways to overcome the food price crisis and its effects on the food chain.
Due to its dispersed structure, the Food Industry is in a weak position when negotiating with the retail sector. [3]
[1] Europa Press Releases: High Level Group to boost competitiveness of the agro-food industry. 12.06.2008
http://europa.eu/rapid/pressReleasesAction.do?reference=IP/08/921&format=HTML&aged=0&
language=EN&guiLanguage=en
[2] Competitiveness of the European Food Industry: An economic and legal assessment.
http://ec.europa.eu/enterprise/food/competitiveness_study.pdf
[3] European Commission. Europa Enterprise and Industry: Promoting Competitiveness in the Agro-Food Industry. 5-6 June 2008.
http://ec.europa.eu/enterprise/food/conferences/intro_en.html
22.06.2008: Belgian soft drinks with Benzene, benzoic acid and benzoates should be banned from acidic beverages [1]
Christof
Van Poucke and colleagues 2008 analysed 134 Belgian soft drinks. The
authors found that ten samples were above the European limit for
benzene in drinking water of 1 µg/L, and one sample had a concentration
of 10.98 µg/L, thereby exceeding the action limit for benzene in soft
drinks of 10 µg /L.
The authors stress that benzene can be
formed when benzoic acid, a food preservative, is combined with
ascorbic acid acidity regulators and interaction with packaging
materials in foods like soft drinks.
Benzene oxidises in the
body to produce an epoxide, benzene oxide, which is not excreted
readily and can interact with DNA to produce harmful mutations.
The
use of preservatives like benzoic acid and benzoates can be avoided by
sanitising filling lines and adopting sound hygienic strategies. Soft
drinks and other beverages are very easy to handle in an sterile
environment.
[1] Van Poucke, Christof ; Detavernier, Christ'l;
Van Bocxlaer, Jan; Vermeylen, Rudi; Van Peteghem, Carlos: Monitoring
the benzene contents in soft drinks using headspace gas
chromatography-mass spectrometry: A survey of the situation on the
Belgian market. Journal of Agricultural and Food Chemistry. 4. June
2008. 56 (12), 4504 – 4510, 2008. DOI: 10.1021/jf072580q
http://pubs.acs.org/cgi-bin/abstract.cgi/jafcau/2008/56/i12/abs/jf072580q.html
22.06.2008: Shelf life testing [1]
Lara
Manzocco and colleagues developed a new shelf life modeling of
photosensitive foods such as beverages highly prone to oxidative
photobleaching, considering different light levels at increasing
temperatures. Bleaching rate, pigment content, and pigment degradation
products were analysed. The authors stress that shelf life testing of
light-sensitive foods must take into proper account the effect of
temperature and light to predicting shelf life of photosensitive foods
under marketing conditions.
[1] Manzocco, Lara; Kravina,
Giuditta; Calligaris, Sonia; Nicoli, Maria Cristina: Shelf Life
Modeling of Photosensitive Food: The Case of Colored Beverages. Journal
of Agricultural and Food Chemistry. Published online ahead of print
6.06.2008. Doi:10.1021/jf800072u
http://pubs.acs.org/cgi-bin/abstract.cgi/jafcau/asap/abs/jf800072u.html
20.06.2008: Rosemary extracts are safe [1]
The Panel of the EFSA considered the use of rosemary extracts as a food additive.
The extracts were:
- F62: rosemary extract produced from dried rosemary leaves by acetone extraction,
- D74: rosemary extract prepared by extraction of dried rosemary leaves by means of supercritical carbon dioxide,
- AR: rosemary extract prepared from a partially deodorised ethanolic extract of rosemary,
- ARD: extract prepared from a deodorised ethanolic extract of rosemary,
- RES: extract which is a decolourised and deodorised rosemary extract
obtained by a two-step extraction using hexane and ethanol.
Four
rosemary extracts, D74, AR, ARD, and RES, were tested for genotoxicity.
Several in vitro genotoxicity studies were performed in both
prokaryotic and eukaryotic test systems and an in vivo mouse
micronucleus test performed with rosemary extract RES. The Panel
concluded that these do not give rise to safety concerns with respect
to genotoxicity of the rosemary extracts.
Based on the margins
of safety identified, the Panel concluded that the use of rosemary
extracts at the proposed uses and use levels would not be of safety
concern.
[1] Use of rosemary extracts as a food additive -
Scientific Opinion of the Panel on Food Additives, Flavourings,
Processing Aids and Materials in Contact with Food. Adopted date:
07/03/2008
http://www.efsa.europa.eu/EFSA/efsa\_locale-1178620753812\_1178714927107.htm
20.06.2008: The hunger hormone Ghrelin defends against depression and anxiety of chronic stress but increases obesity. [1]
Zigman
and Lutter found that the "hunger hormone" ghrelin might also defend
against symptoms of stress-induced depression and anxiety, but also
increases food intake and body weight.
Ghrelin is produced in
the gastrointestinal tract, and sends a hunger signals to the brain.
Blocking the effect of ghrelin might control weight, by decreasing food
intake and increasing energy expenditure, but may also increase anxiety
and depression.
Mice bred to model depression (referred to as
chronic social defeat stress) had persistently increased ghrelin
levels. A ghrelin receptor in the brain is linked to growth hormone and
called the growth hormone secretagogue receptor (Ghsr). Mice bred to
lack this receptor (Ghsr-null mice) showed even more deleterious
effects of chronic defeat.
The authors concluded that hormones
associated with appetite and hunger may co-ordinate an entire
behavioural response to stress and probably affect mood and energy
levels. The findings may help to understand the conditions like
anorexia nervosa, where calorie restriction and weight loss could have
an anti-depressant effect and be reinforcing for this illness. [2]
[1]
Zigman, Jeffrey; Lutter, Michael: Hunger hormone increases during
stress, may have antidepressant effect. Eurekalert. 15.06.2008
http://www.eurekalert.org/pub_releases/2008-06/usmc-hhi061208.php
[2]
Lutter, Michael,;Sakata, Ichiro; Osborne-Lawrence, Sherri; Rovinsky,
Sherry A.; Anderson, Jason G.; Jung, Saendy; Birnbaum,
Shari;Yanagisawa, Masashi; Elmquist, Joel K.; Nestler, Eric J.; Zigman,
Jeffrey M.: The orexigenic hormone ghrelin defends against depressive
symptoms of chronic stress. Nature Neuroscience. Published online: 15
June 2008 | :10.1038/nn.2139
http://www.nature.com/neuro/journal/vaop/ncurrent/abs/nn.2139.html
20.06.2008: Volatile compounds of coffee aroma alleviate sleep deprivation stress and have antioxidant activities [1]
There are about 900 volatile compounds in the aroma of roasted coffee beans.
Han-Seok Seo and colleagues 2008 found that the volatiles in coffee
induce changes in the expression of messenger RNA (mRNA) and protein
levels in the rat brain, resulting in antioxidant or stress relaxation
activities.
mRNA are messenger molecules that indicate when a
gene is being expressed. There are 11 genes which are important to
brain function. When the rats were exposed to the aroma of coffee, the
mRNA for nine of the genes was restored to near normal levels, and
pushed to above normal levels for two: GIR which is involved in
neuro-endocrine control, and NFGR, which controls oxidative stress.
The
authors concluded that it is not yet known if the results may be
translated to humans, however, these results may explain why coffee is
preferred by humans when they need to stay awake. The volatiles of the
coffee aroma may help alleviate the stress of the sleep deprivation
caused by sleep deprivation changing the mRNA and protein expression
levels of the rat brain, and have antioxidant activities.
[1]
Seo, Han-Seok; Hirano, Misato; Shibato, Junko; Rakwal, Randeep; Hwang,
In Kyeong; Masuo, Yoshinori: Effects of Coffee Bean Aroma on the Rat
Brain Stressed by Sleep Deprivation: A Selected Transcript- and 2D
Gel-Based Proteome Analysis. J.Agric.Food Chem. 56(12),4665-4673, 2008.
doi:10.1021/jf8001137. Web Release Date: June 3,
http://pubs.acs.org/cgi-bin/abstract.cgi/jafcau/2008/56/i12/abs/jf8001137.html
19.06.2008:
Vitamins C, E, and beta-carotene from fruits and vegetables but not
from supplements reduce risk of Barrett's esophagus [1]
Ai
Kubo and colleagues 2008 evaluated the associations among antioxidants,
fruit and vegetable intake, and the risk of Barrett's esophagus, a
potential precursor to esophageal adenocarcinoma.
The authors
found that dietary antioxidants, fruits, and vegetables are inversely
associated with the risk of Barret's esophagus, while no association
was observed for supplement intake. Kubo and colleagues suggest that
fruits and vegetables themselves or a not yet identified compound of
fruits and vegetables may reduce the risc of esophageal cancer.
[1]
Kubo, Ai; Levin, Theodore R.;G. Block, Rumore, Gregory J.; Quesenberry,
Jr,,Charles P. Buffler, Patricia; Corley, Douglas A.: Dietary
Antioxidants, Fruits, and Vegetables and the Risk of Barrett's
Esophagus. American Journal of Gastroenterology. Volume 103, Pages
1-10, doi: 10.1111/j.1572-0241.2008.01838.x
http://www.blackwell-synergy.com/doi/abs/10.1111/j.1572-0241.2008.01838.x
19.06.2008: Ireland, supplements and the EU
Irish
Association of Health Stores, health store retailers as well as food
supplement manufacturers and wholesalers are campaigning against EU
regulations.
The European Referendum Initiative: The
European Referendum Initiative, sustained by six organizations, say
that European citizens are not given the right to be directly involved
in political decision-making, degenerating into a dictatorship where
democracy, freedom of choice and the privacy rights of individuals are
violated, and the interests of big business over those of its own
citizens are favoured. [1]
Irish Association of Health Stores: The Irish Association of Health Stores, in a meeting of its National Council announced to oppose the Lisbon Treaty.
In
its press release of 9 June 2008 the IAHS says that Europe has not been
good for the natural products industry, or for freedom of choice in
healthcare, alleging that the Lisbon Treaty seems set to further
facilitate erosion of individual rights and choices.
The
Association point to the Food Supplements Directive and the Traditional
Herbal Medicinal Products Directive saying that these regulations work
at the expense of small enterprises and the natural products sector.
The Association also says that trade regulations within the EU are
drawn up to favour big business.
The Irish Association of
Health Stores IAHS campaigned for years against regulations of Food
supplements and functional foods calling them as highly restrictive.
IHAS admits that the EU constitution, which was rejected by the Irish
referendum, was not directly relevant to food industry. The opposition
base on rejecting further centralisation of laws in Europe. [2]
The IHAS Petition for higher level vitamin and mineral supplements: Freedom of healthcare choice [3]
We
require that the Irish government and EU commission respect and retain
our right as consumers to exercise freedom of choice in healthcare.
Specifically
we require that our right to access the higher level vitamin and
mineral supplements, which have been available in Ireland and elsewhere
for the past 40 years, should not be eroded as is currently proposed
under the Food Supplements Directive and recommended by the Food Safety
Authority of Ireland.
Distorted facts
The
IAHS says that the issue highlighted in the Petition for higher level
vitamin and mineral supplement and the video
“saveoursupplementsireland.com" [4]
only a part of the restrictions on freedom of choice in healthcare to
come with the directive on herbal products (Traditional Herbal
Medicinal Products Directive) and a regulation on nutrition and health
claims (NHCR). [2]
However,
these regulations are meant to protect the consumer from unsafe high
dosages and misleading informations of claims for which there are no
scientific proofs. These regulations base on worldwide accepted facts
and are found in the Codex Alimentarius of the United Nations.
Freedom of access to higher doses
No
European regulations denies the right of Irish consumer to take 2 or
ever ten pills of the supplements, on its own risk, double or even
tenfold doses of vitamins and minerals may so be achieved. The European
Union, however, has the obligation to protect those who are concerned
about long-term intoxication resulting of unhealthy high
supplementation.
Medicinal herbs over the counter [5] [6]
The
Directive on Traditional Herbal Medicinal Products, or more precisely,
Directive 2004/24/EC of the European Parliament and of the Council of
31 March 2004 amending, as regards traditional herbal medicinal
products, Directive 2001/83/EC on the Community code relating to
medicinal products for human use is an European Union directive that
was agreed in April 2004 and came into force on 30th October 2005.
The
European medicinal herbs regulation has no restrictions on herbs or
claims for products which were on market for 30 years in the EU (or at
least 15 years in the EU and 15 years elsewhere).
The
Directive requires traditional, over-the-counter herbal remedies which
are not included in the 30 years rules, must assure standards of safety
and quality and for regulations to be standardised throughout the
European Union, or have to be withdrawn from sale.
The knowledge
of medicinal herbs is as ancient as history of mankind is. New-modern
herbs and their claims based on assumptions which cannot stand
scientific proves deceive those who do not get the effects which are
being advertised.
The Constitution of the European Union gives
strength to Council to fight back US hormone meat, GM rice from USA,
protects the consumer against the excesses of the WTO and looks after
food safety. Democracy must respect the decision of the majority
otherwise a community brakes appart. The European Union, with a free
trade of foods in their borders increased the freedom of choice of the
consumer bringing foods from 27 countries on the shelves of food stores
insuring a high standard of safety.
[1] European Referendum Initiative: Consumer organizations launch campaign
demanding right to referendums. Press Release - 3 March, 2008
http://www.eu-referendum.org/english/press_releases/20080303_launch_campaign.html
[2] Irish Association of Health Stores IAHS: 9 Jun 2008 - IAHS Heeds D' Estaing's Words
http://www.irishhealthstores.com/
[3] IAHS Care 2 Petition Site: Help save our supplements: Freedom of choice in heathcare.
http://www.thepetitionsite.com/2/help-save-our-supplements
[4]
Save Our Supplements Ireland.com: Exposed! The scandal of proposed EU
regulations to restrict your access to safe vitamin and mineral
supplements. Watch the 60 seconds video at:
http://www.youtube.com/watch?v=5JOBY0KDERY
[5] Directive 2004/24/EC of the European Parliament and of the Council of 31 March 2004
amending, as regards traditional herbal medicinal products, Directive 2001/83/EC on the
Community code relating to medicinal products for human use
http://en.wikipedia.org/wiki/European_Directive_on_Traditional_Herbal_Medicinal_Products
[6]
Directive 2001/83/EC of the European Parliament and of the Council of 6
November 2001 on the Community code relating to medicinal products for
human use.
http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2001:311:0067:0128:EN:PDF15.06.2008:
19.06.2008: Reasons of the Irish No to Europe[1]
Hubert Kleinert in an article in German Spiegel, cites four reasons of the Irish NO to the European Constitution:
Unconsciousness of what they were voting
1.- People find Europe intransparent. They do not understand how the EU functions. Get informed about the Treaty of Lisabon. [2] [3]
2.-
Lacking public dialogue which is hindered because of 27 different
languages. Translation of all regulations in 27 languages are being
provided. All Members of the European Parliament (MEPs) maintain sites
with specific informations in the language of their country. [4]
3.-
The unconditional competition philosophy of the market. That is how
globalisation works. The EU protects the consumer through its
Competition Law. [5]
4-
Bad image of the politicians. All politicians are elected by the
people. There is no uniform voting system for the election of MEPs;
rather, each member state is free to choose its own system. [6]
[1] Kleinert, Hubert: Warum die Iren nicht die Deppen Europas sind. Spiegel Online 19.06.2008.
http://www.spiegel.de/politik/ausland/0,1518,560575,00.html
[2] The Treaty of Lisabon at a glance
http://europa.eu/lisbon_treaty/glance/index_en.htm
[3] Full text of the Treaty of Lisabon
http://europa.eu/lisbon_treaty/full_text/index_en.htm
[4] Your Members of the European Parliament. Contacts
http://www.europarl.europa.eu/members/public.do?language=en
[5] Wikipedia: European Community competition law
http://en.wikipedia.org/wiki/European_Community_competition_law
[6] Wikipedia: Members of the European Parliament, election
http://en.wikipedia.org/wiki/Members_of_the_European_Parliament
Rising demands of oilseeds increase pressure on biodiversity of producers [1]
The
USDA report on oilseeds says that vegetable oil prices will likely
remain above historic averages during 2008/09 as demand remains strong
primarily due to surging growth in the developing world. Prices for all
vegetable oils have double or tripled over the last 18 months as
supplies were restricted due to various production shortfalls and
policy imposed - export impediments.
According to USDA oil
importers, particularly China and India, will look toward palm oil to
satisfy demand for vegetable oil as ending stocks of major soy oil
exporters (Argentina, Brazil, and the United States) are forecast down
2 percent from last year.
Wang Yinji, of the Chinese grains
company Cofco says that Chinese vegetable oil consumption will rapidly
rise for a few years because per capita consumption of 17 kilograms a
year is below the world average, compared with 25 Kg in Taiwan and
nearly 40 Kg in the USA. [2]
This
increases the pressure on the ecology of Brazil which tries to expand
its soy fields together with increasing bio-fuel programs.
[1] USDA: Oilseeds: World Markets and Trade. June 2008
http://www.fas.usda.gov/oilseeds/circular/2008/June/oilseedsfull0608.pdf
[2] China.org.cn: China to import more cooking oil. (Shanghai Daily November 21, 2007)
http://china.org.cn/english/business/232617.htm
15.06.2008: Organic milk for everyone [1]
Arla
Foods is strong in UK, Sweden, Denmark aims to increase its business
with organic milk, cheese and yoghurt rising its payouts to farmers to
avoid shortfall. The organic market of Denmark and Sweden are dominated
by Arla which looks at the immense potential of Germany. Meanwhile
traditional farmers in Germany and the Netherlands are fighting to
survive while being underpaid.
The company claims to be the world’s largest producer of organic milk products. [2]
Arla
Foods expands now its production sites on eight additional strategic
countries: Germany, Poland, Russia, Middle East, United States, Canada,
Spain and Greece. In the Middle East the company is present in Dubai,
while jobs are lost in their main production site at Copenhagen.
Regional organic sustainable infrastructure are being dismantled by by all overlapping corporations.
[1]
Arla Foods: Arla streamlines its international organisation: Arla
streamlines its organisation for the international consumer markets.
The ambition is to come closer to consumers and customers. At the same
time Arla focuses on eight markets including the Middle East
http://www.arlafoods.com/APPL/HJ/HJ202COM/HJ202D01.NSF/O/9E404F95E52599D3C1257452002E6C02
[2]
Arla Foods: Arla to make organic production even more attractive From
July 1, Arla Foods is to increase the payment to its organic
co-operative members in both Denmark and Sweden to attract more organic
producers.
http://www.arlafoods.com/appl/HJ/HJ202COM/HJ202D01.NSF/O/19879E5DC37253B5C12574650045F368
15.06.2008: Alliance between GM and organic farming [1]
According
to Pamela Ronald says that combining genetic technology with organic
farming is the future of global food production. However, the animosity
between the two hardened fronts have to be overcome. The plant
pathologist says that genetically modified seeds grown using organic
agricultural methods can significantly increase yields whilst reducing
the use of environmentally damaging chemicals. The author says to meet
increasing food demand genetic engineering and organic farming should
be combined. She stresses that after more than a decade of genetically
engineered crops, and more than 30 years of organic farming, we know
that neither method alone is sufficient to solve the problems faced -
and caused - by agriculture.
Pamela Ronald stresses that when
genetic engineering hits its limits, though, organic farming can help.
For example, the Bt cotton that transformed Chinese farming only kills
caterpillars of some species, so it cannot be a stand-alone solution
for general insect control. In fact, after seven years of pesticide
reductions in Bt cotton fields in China, populations of other insects
increased so much that farmers had to resume spraying certain
insecticides. Organic farmers, by contrast, control these secondary
pests by introducing beneficial insects that feed on the pests and by
rotating crops to reduce the overall pest populations.
The IAAKSTD Report [2]
The
International Assessment of Agricultural Knowledge, Science and
Technology for Development report, published in April 2008 also
supports blending both systems to achieve food security.
The report
reminds that there is a world of asymmetric development, unsustainable
natural resource use, and continued rural and urban poverty. The report
calls for a shift of the conventional agriculture to recognize and give
increased importance to the multifunctionality of agriculture,
accounting for the complexity of agricultural systems within diverse
social and ecological contexts.
It is, however, important for
big corporations to abandon the policy of highes earnings and cooperate
with the development of traits adapted to regional needs. This is a
goal of the united scientific world has to face , integrating the
research of international universities and the financial cooperation of
the established corporations. One smal start may be Monsanto and BASF
releasing transgene corn traits for Africa:
Monsanto and BASF rethinking sustainability [3]
According
to a press release of Monsanto, the company, together with BASF, will
provide drought-tolerance corn transgenes that they have developed
through their collaboration. These contributions will be provided
without royalty. This will go along with the work of African
Agricultural Technology Foundation.
[1] Pamela Ronald: The new
organic. The future of food may depend on an unlikely marriage: organic
farmers and genetic engineering. March 16, 2008
http://indica.ucdavis.edu/news/filestorage/The%20new%20organic%20-%20The%20Boston%20Globe.pdf
[2] Executive Summary of the Synthesis Report of the
International Assessment of Agricultural Knowledge, Science and Technology for Development (IAASTD)
http://www.agassessment.org/docs/SR_Exec_Sum_210408_Final.pdf
Get all reports of IAASTD :
http://www.agassessment.org/index.cfm?Page=IAASTD%20Reports&ItemID=2713
[3]
Monsanto: Drought Tolerant Corn WEMA Project News Release March 2008.
African Agricultural Technology Foundation to Develop Drought-Tolerant
Maize Varieties for Small-Scale Farmers in Africa. Long-term goal of
public-private partnership to reduce crop failure, alleviate hunger and
poverty. African Agricultural Technology Foundation.
http://www.monsanto.com/droughttolerantcorn/WEMA.asp
14.06.2008:Gum arabic replacement[1]
Climate and political factors in Sudan and Nigeria cause insecurity in the supply of gum arabic
Sugar beet pectin was found by Siew and Williams 2008 to be a substitute being, however, more expensive than gum arabic.
Studying
the content of protein and ferulic acid of the sugar beet pectin
fraction the authors found that one or both of these two functional
groups adsorb onto the surface of the oil droplets and stabilize the
emulsions.
The authors concluded that compared to those made with
gum arabic, the emulsion samples made with sugar beet pectin samples
exhibited similar (or even slightly higher) stability.
[1] Siew,
C.K.; Williams P.A.: Role of Protein and Ferulic Acid in the
Emulsification Properties of Sugar Beet Pectin. Journal of Agricultural
and Food Chemistry Volume 56, Number 11, Pages 4164-4171
Doi:10.1021/jf073358o
http://pubs.acs.org/cgi-bin/abstract.cgi/jafcau/2008/56/i11/abs/jf073358o.html
14.06.2008: U.S. bio ethanol industry result in threefold mycotoxins contamination in feed {1}
High
levels of mycotoxins in maize-based ethanol co-products up to three
times compared with grains, are expected by Wu and Munkvold 2008. The
co-products are mostly dried distillers' grain and solubles or wet
distillers' grains which are fed to livestock. The authors estimate
that the mycotoxins from dried distillers' grain and solubles, mainly
fumonisins, may result in loss of up to 293 million USD/y to the swine
industry from weight gain reduction. Other stakeholders are also
affected if mycotoxin contamination in both pre- and postharvest maize.
will not be controlled.
The toxicity of the fumonisins,
fumonisin B1 (FB1), fumonisin B2 (FB2), and fumonisin B3 (FB3),
produced by Fusarium moniliforme to poultry was studied by Henry and
Wyatt. The authors found that the 50% lethal dose for FB1, when
injected into the air cell of embryonating chicken eggs, was 18.73
microg per egg. [2]
Synergistic effect of fumonisins on the toxicity of fusaric acid [3]
Fusaric acid, only moderately toxic to the chicken egg, was found by
Bacon, Porter and Norred 1995 to have its toxicity increased due to the
synergistic effect of fumonisin B1 and other fusaria toxins found on
corn and other cereals. The authors concluded that fusaric acid might
play a role in enhanced and unpredicted toxicity in mammalian systems
if it is consumed with other mycotoxins.
Fumonisins in quail rations [4]
Butkeraitis
and colleagues 2004 found that exposure to FB 1 at concentrations equal
or more than 50 mg/kg could adversely affect quail performance. The
authors stress the importance of controlling fumonisin contamination of
quail rations.
Human tolerable Daily Intake is 800 ng/kg bw/day of FB1.
FDA sees fumonisins residues as not a public health concern [5]
The
FDA concluded in residue Studies in 2000 that fumonisins are poorly
absorbed 'orally' in all species tested to date. Oral bioavailability
averaged about 4% in swine and 0.7% in laying hens. Most of the
ingested FB1and FB2 is excreted in the feces unchanged. The FDA
believes fumonisin residues in meat, milk and eggs will likely not be a
public health concern.
Exposure Assessment by the Australian FSA [6]
Maize is the only commodity that contains significant amount of fumonisins (IPSC, 2000). Estimated
mean dietary intakes of fumonisin B1 based on regional diets and published distributions of
concentrations of fumonisin B1 in maize, indicating a mean intake of fumonisin B1 ranging from 0.2
μg/kg bw/day in European-type diet to 2.4 μg/kg bw/day in the African diet (WHO, 2001c).
Fumonisin B1 is not well absorbed by poultry and should not contribute significantly to human dietary
exposure.
Risk Characterisation:
Secondary exposure to fumonisin B1 through consumption of poultry meat
products derived from poultry fed fumonisin B1-containing feed,
presents a negligible risk to the consumer
[1] Wu, Felicia;
Munkvold, Gary P. : Mycotoxins in Ethanol Co-products: Modeling
Economic Impacts on the Livestock Industry and Management Strategies.
Journal of Agricultural and Food Chemistry. Volume 56, Number 11, Pages
3900-39011 doi:10.1021/jf072697e
http://pubs.acs.org/cgi-bin/abstract.cgi/jafcau/2008/56/i11/abs/jf072697e.html
[2]
Henry, M. H.; Wyatt, R. D.: The toxicity of fumonisin B1, B2, and B3,
individually and in combination, in chicken embryos. Poultry Science,
Vol 80, Issue 4, 401-407
http://ps.fass.org/cgi/content/abstract/80/4/401
[3]
Bacon, C. W. ; Porter, J. K. ; Norred, W. P. ; Toxic interactions of
fumonisin B1 and fusaric acid measured by injection into fertile
chicken egg. Mycopathologia. 1995, vol. 129, nr 1, pp. 29-35 (47 ref.)
http://cat.inist.fr/?aModele=afficheN&cpsidt=3597478
[4]
Butkeraitis, P.; Oliveira, C.A.F.; Ledoux, D.R.; Ogido, R.; lbuquerque,
R. A; Rosmaninho, J.F. ; Rottinghaus, G.E.: British Poultry Science.
Volume 45, Number 6, December 2004 , pp. 798-801(4) http://www.ingentaconnect.com/content/tandf/cbps/2004/00000045/00000006/art00010
[5] FDA: Background Paper in Support of Fumonisin Levels in Animal Feed. June 6, 2000
http://www.cfsan.fda.gov/~dms/fumonbg2.html
[6]FSA
Australia New Zealand: Scientific Assessment of the Public Health and
Safety of Poultry Meat in Australia Food Standards Australia New
Zealand November 2005
http://www.foodstandards.govt.nz/_srcfiles/P282_Poultry%20_%20DAR%20Attach3.pdf
14.06.2008: Turning corn fiber into ethanol [1]
Hans
Van Leeuwen, developed a process that can convert corn fiber, a
byproduct of the wet milling process that produces corn syrup, into
fuel-grade ethanol. It uses a mould which produces enzymes that break
down corn fibre into simple sugars which can be fermented into ethanol.
This process may also be applied to distillers dried grains, a
byproduct of the dry milling process that's typically used to convert
corn kernels into ethanol.
According to the authors ethanol is
produced grinding corn kernels and adding water and enzymes. The
enzymes break the starches into sugars. The sugars are fermented with
yeasts to produce ethanol which is distilled.
The authors say that
for every gallon alcohol produced there are six gallons of leftovers
called stillage. The solids are removed by centrifugation, which may be
dried and sold as cattle feed as distillers dried grains.
Half of
the remaining liquid, known as thin stillage is used for next
fermentation and the other half is evaporated and blended with
distillers dried grains to produce distillers dried grains with
solubles.
The researchers used a fungus, Rhizopus microsporus, to
remove about 80 per cent of organic material and the solids so the
whole thin silage may be used in the next fermentation batch. The
fungus which grows during the process is rich in protein, certain
essential amino acids and other nutrients and may be added to
distillers dried grains as feed for hogs and chicken.
This process improves alcohol yield and reduces energy needed in the process.
[1] Iowa State University: Iowa State researchers use fungus to improve corn-to-ethanol process. 25.May 2008
http://www.public.iastate.edu/~nscentral/news/2008/may/fungus.shtml
13.06.2008: European Constitution as layed down by the Treaty of Lisbon rejected by Irish referendum [1]
It
is a hard slap on democracy, when a small minority is able to stop
themajority of the European population. Ireland was a poor developing
country and is now, thanks to heavy subventions of the EU, on the way
to become a high tech country.
Not ratifying the Treaty of
Lisbon brings serious problems to handle WTO, pressure from USA to
allow GM food and to harmonize European food Law.
Ireland argues
with irrational slogans like "People died for your freedom. Don´t trow
it away." This does not comply with the European spirit.
The European Commission should leave those minorities outside and create its own block of those who ratified the Constitution.
[1] Los Angeles Times: Ireland sees growing opposition to European constitution
The
June 12 vote on the Lisbon Treaty now seems less certain, as opposition
groups, some businessmen and farmers raise concerns about sovereignty.
http://www.latimes.com/news/printedition/suncommentary/la-fg-treaty1-2008jun01,0,871786.story
13.06.2008: Extract from red yeast Chinese rice XZK reduced cardiovascular events and death [1]
David
M. Capuzzi and colleagues 2008, report that treatment with XZK
decreased CV and total mortality by 30% and 33%, the need for coronary
revascularization by 1/3.
According to the authors total and
low-density lipoprotein cholesterol and triglycerides were lowered, and
the good high-density lipoprotein cholesterol levels were raised. They
concluded that long-term therapy with XZK decreased the recurrence of
coronary events. New cardiovascular events and deaths were reduced.
[1]
Lu, Zongliang; Kou, Wenrong; Du, Baomin; Wu, Yangfeng; Zhao, Shuiping;
Brusco, Osvaldo A.; Morgan, John M.; Capuzzi, David M. and Chinese
Coronary Secondary Prevention Study Group: Coronary artery disease:
Effect of Xuezhikang, an Extract From Red Yeast Chinese Rice, on
Coronary Events in a Chinese Population With Previous Myocardial
Infarction. The American Journal of Cardiology. Volume 101, Issue 12,
15 June 2008, Pages 1689-1693 doi:10.1016/j.amjcard.2008.02.056
http://www.ajconline.org/article/S0002-9149(08)00353-6/abstract
12.06.2008: Clones and foods derived from them [1]
Animal
cloning is an emerging technology in the EU and well established in the
US. Food derived from cloned animals will enter the food chain across
the world.
The FSA exploring the perceptions of animal cloning
and to identify what the key issues and areas of concern/uncertainty
are, particularly in relation to food.
FSA concluded that
consumer struggled to identify any convincing benefits of the technique
and felt that the only "winners" were likely to be the biotechnology
companies, livestock breeders, farmers or food retailers and were
concerned that the only reason for introducing animal cloning was a
financial one. They questioned whether there were really any benefits
for consumers.
Views on Labelling
FSA found that the consumer call for all food derived from cloned animals and their offspring to be clearly
labelled. The question arouse how far removed an animal needs to be from a cloned ancestor before it is considered ‘normal’.
Cloning in USA [2]
In the US, the Food and Drug Administration has concluded that "meat and milk
from cow, pig, and goat clones and the offspring of any animal clones are as safe as
food
we eat every day."Labelling of cloned animals and food derived from the
, like meat, eggs and milk in USA will not be required. Cloned foods
already entered the food chain.
New Zealand [3]
According
to the New Zealand Food Safety Authority, there is no accepted
scientific evidence to suggest that food from cloned animals is any
less safe than food from non-cloned animals.
Denmark
Denmark, has specific legislation on the cloning of farm animals.
EU
In
the EU any food product derived from cloned animals has to be subjected
to a safety evaluation and needs to be approved by all European Union
(EU) Member States as a novel food before it could be
legally marketed.
Intellectual property issues [4]
The Group stresses that it should be clarified whether the exclusion clauses in Directive 98/44/EC
(Art. 6d) on patentability of biological inventions and the EPO rules (23 d) to animal cloning for food
apply.
The European Food Safety Authority (EFSA)
The
EFSA examined the question of the safety of clones, their progeny and
the environment and found them as safe. However, cloning, as with other
assisted reproduction technologies, could unintentionally affect the
genetic diversity by increasing the proportion of a specific genotype
within a given population.
Assisted reproductive techniques (ARTs)
Assisted reproductive techniques (ARTs) are:
Click picture to enlarge view
Artificial Insemination
Involves the collection of semen from bulls which can then be used to artificially inseminate cows.
It is possible to freeze the semen, store it for longer and make it more widely available. Genetic diversity is not affected.
Oestrus Synchronisation
Involves giving hormone implants and injections to ensure a group of cows are ready for
breeding at the same time, being used together with artificial insemination. Genetic diversity is not affected.
Embryo Transfer
Just
as artificial insemination is used to produce lots of calves from a
single, prize bull, embryo transfer is used to produce more offspring
from a prize cow stimulated with a hormone to produce a number of eggs
at once. The cow is then mated and many of the eggs are fertilised and
start
to develop. The embryos are flushed out surgically and implanted into the uterus of surrogate
mothers where they are brought to term. Genetic diversity is not affected.
In Vitro Fertilisation
This is a similar process to embryo transfer except the unfertilised eggs of the prize cow
are fertilised in an incubator before being transferred to surrogate mothers. Genetic diversity is not affected.
Sexed Semen
The purpose of this is to produce a higher proportion of female calves. Genetic diversity is not affected.
[1] FSA Study: Animal Cloning and Implications for the Food Chain. Findings of Research Among the General Public
http://www.food.gov.uk/multimedia/pdfs/clonereport.pdf
[2] U.S. FDA: Center for Veterinary Medicine: Animal Cloning
http://www.fda.gov/cvm/cloning.htm
[3] New Zealand Food Safety Authority: Food from cloned animals.
http://www.nzfsa.govt.nz/policy-law/publications/policy-statements/food-cloned-animals/food-from-
cloned-animals-final.htm#P31_2524
[4]
Directive 98/44/EC of the European Parliament and of the Council of the
European Union on the legal protection of biotechnological inventions
of 6 July 1998.
http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:1998:213:0013:0021:EN:PDF
11.06.2008:
Bisglycinates as sources of copper, zinc, calcium, magnesium in foods
and as food supplements are safe, safety unclear of chromium glycinate
nicotinate complex [1]
The
Panel of the EFSA published an opinion which says that the use of
copper bisglycinate chelate, zinc bisglycinate chelate, calcium
bisglycinate chelate, and magnesium bisglycinate chelate as a source of
the specific element for nutritional purposes and food supplements is
not of safety concern.
The Panel could not reach a conclusion on the safety of chromium glycinate nicotinate complex, due to lack of information.
[1]
EFSA: Scientific Opinion of the Panel on Food Additives, Flavourings,
Processing Aids and Materials in Contact with Food on a request from
the Commission on certain bisglycinates and glycinate nicotinate as
sources for copper, zinc, calcium, magnesium and chromium. The EFSA
Journal (2008) 718, 1-26
http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753820_1178713218484.htm
10.09.2008: Bioavailability of zinc gluconate salts compared with zinc from yeasts
Zinc
is, after iron, the most important trace elements in the body,being
related to a healthy immune system, influence memory, muscle strength
and endurance in adults.
According to Thomas Tompkins and colleagues
compared the bioavailability of zinc gluconate and zinc from yeasts in
two studies presented in 2007.
The first study found zinc
yeast to have significantly less loss in the faeces, accounting for a
gain in net zinc balance, while, in comparison, zinc gluconate
supplementation resulted in net loss of zinc through the faeces. [1]
In
the second study Tomkins and colleagues wrote that zinc-enriched yeast
was 3.7 times more bioavailable than the zinc gluconate and that
copper-enriched yeast was 1.4 times more bioavailable than the Cu
gluconate. Lallemand Health Ingredients is waiting for the approval
from EFSA for the mineral enriched yeast supplement. [2]
[1]
Vinson, Joe A.; Tompkins, Thomas A. Agbor, Gabriel A.: Comparative
Bioavailability of Mineral-enriched Gluconates and Yeast in Rat Liver
After Depletion-Repletion Feeding. Biological Trace Element Researche ,
Humana Press. Volume 118, Number 2 / September, 2007 104-110 (7).
http://www.ncbi.nlm.nih.gov/pubmed/17873352
[2]
Tompkins, Thomas A.; Renard, Nadine E.; Kiuchi, Akira: Clinical
Evaluation of the Bioavailability of Zinc-enriched Yeast and Zinc
Gluconate in Healthy Volunteers. Biological Trace Element Researche ,
Humana Press, (Humana Press). Volume 120, Numbers 1-3 / December 2007
pp 28-35 (8)doi: 10.1007/s12011-007-0072-2
http://www.springerlink.com/content/n138537440760645/09.06.2008
09.06.2008: European Union draft of Renewable Energy Directive critics
Carbon permits [1]
Claude
Turmes, European Parliament Rapporteur on the Renewable Energy
Directive says that the trade of certificates described in article
eight of the proposed directive, can be limited by the Commission
according to article nine. to protect the national support schemes.
However, turmes sys that investors could say this is contrary to
article 28 and 30 [EC Treaties] relating to the free movement of goods.
Business with Carbon Permits is already flourishing [2] [3]
The
North-Pool stock exchange will trade CO2 futures and use the
trans-Atlantic potential. Carbon permits cost in Europe 27 EUR/Ton CO2
and the price is expected to rise up to 40 EUR, meanwhile the US
permits cost only 4.7 EUR (7 USD). A good business for North-Poole and
Richard Sandor, head of the London-based Climate Exchange PLC.
Doha Bank in Qatar [4]
The
Doha Bank, a major Qatari private commercial bank, is the pioneer in
financing carbon trading deals in cooperation with Japanese companies
for a market trading greenhouse gas emission rights.
Research on effects of biofuel production [5]
According
to a study by order of the European trade body for the biscuit and
confectionery industry (CAOBISCO) the 10 per cent mandatory target for
the inclusion of biofuels in transport fuel by 2020 will have serious
effects on environment and food prices. According to the study global
demand for agricultural commodities and erratic weather already
contributed considerably to the dramatic price increases in raw
materials worldwide.
The study stresses that the EU is unable to
cope with the demand of 10 per cent biofuels and will becomes a
net-importer of grains, moving from 10 million tonnes of exports up to
32 million tonnes of imports, and up to 50 per cent of vegetable oils
will be imported in 2020.
The study calls for the development
of second – generation (non-food crop based biofuels, such as waste
from agricul
